Polynucleotides are an injectable, skin-boosting, regenerative treatment that has gained popularity in recent years. Polynucleotides are made up of chains of nucleotides, which are the building blocks of DNA. When used in aesthetics, polynucleotides are typically derived from the sperm of salmon or trout and are then purified and sterilised for medical use. They are then injected into the skin to provide instant hydration and long-term bio-remodelling.